mycoplasma pneumonia in cerebrospinal fluids of febrile children with neurologic manifestations: a cross sectional study, tehran, iran
نویسندگان
چکیده
conclusions: even, very low amount of csf-igg with good specificity (90%); could differentiate cases and controls (p = 0.000). the csf-igg test (sensitivity 70%, npv 28.8%) was weak for ruling out the m. pneumonia in cases. positive pcr was rare (2%) in csf of cases and controls but is more reliable for diagnosing the recent m. pneumonia infection. we prefer to assay the csf for both serology and pcr in highly suspicious cases. anti-microbial or immune modulating therapies had possible benefits. results: positive pcr found in 1 case with guillan barre syndrome (1/53; 2%) and none of controls; igg-csf level (cut off 0.0025) had significant difference between cases and controls (kappa = 0.27, p value = 0.000). the lowest and highest igg level observed in aseptic meningitis, and convulsive cases respectively. 73% sensitivity; 90% specificity; 100% variance (ppv); 28.8% net present value (npv) determined for igg-csf test. materials and methods: this cross sectional study was done in pediatric wards of rasoul hospital in tehran between 2008 - 2010 upon 55 febrile cases with neurological signs and 10 controls with normal csf (simple febrile seizure). the csf samples tested for m. pneumonia dna (pcr); and immune globulin g (igg) level. chi square values < 0.05 were considered statistically significant. background: the clinical spectrum of mycoplasma pneumoniae cns diseases had a wide range. encephalitis and meningoencephalitis are the most frequent neurological manifestations, but cases of optic neuritis, transverse myelitis, guillain-barré syndrome (gbs), etc. have been reported objectives: to determine the role of m. pneumonia (using pcr and serologically test) in cerebro spinal fluid (csf) in febrile children with neurologic manifestations (in comparison with normal csf).
منابع مشابه
prevalence of atopic dermatitis in children with type 1 diabetes mellitus in southeastern of iran (kerman province): a case-control study
چکیده ندارد.
15 صفحه اولSearching Mycoplasma pneumonia by serology & PCR in children with adenoid hypertrophy and rhinosinusitis: A case control study, Tehran, Iran
BACKGROUND AND OBJECTIVES Chronic infection in childhood is a leading cause of adeno-tonsillectomy. The aim of this study was to determine the role of M. pneumoniae in children with rhino sinusitis and adenoid hypertrophy. METHOD AND MATERIAL This case - control study was carried out in the pediatric and ENT wards of Hazrat Rasul Hospital, Tehran, Iran (2007-2009). In this trial, we investiga...
متن کاملSearching the H. pylori serology & PCR in children with adenoid hypertrophy and rhino sinusitis: a cross sectional study, Tehran, Iran
متن کامل
Cerebrospinal Fluid Indices in Children with Febrile Convulsion
Background and Objective: Febrile convulsions (FC) are the most common seizure disorders in children. Lumbar puncture should be considered in any case with FC who is suspected to intracranial infections. This study determined white blood cell and polymorphonuclear cell counts, protein and glucose levels in cerebrospinal fluids (CFS) of children that were hospitalized with FC. Methods: In this ...
متن کاملQuality of life in patients with psoriasis: A cross-sectional study in a dermatology referral hospital in Tehran, Iran
Background: Psoriasis is a chronic skin disorder that can significantly affect a patient’s quality of life (QoL). The goal of this study was to determine the QoL in patients with psoriasis and to investigate the correlation between the QoL, demographic data, and clinical severity of psoriasis.Methods: This prospective, cross-sectional study was conducted from April 2014 to January 2015. One hun...
متن کاملNeurologic manifestations in children and adolescents with chronic kidney diseases
Background and Objective: Chronic renal failure (CRF) may have many effects on nervous system and manifest as headache, seizure, dialysis disequilibrium syndrome, cerebral hemorrhage, hypertensive encephalopathy, uremic neuropathy, and some neurologic complications of transplantation. In this present study we investigate neurologic disorders in children with CRF. Methods: In this descriptive...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
jundishapur journal of microbiologyجلد ۶، شماره ۹، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023